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What is CBT and eCBT?


Cognitive Behavioral Therapy (CBT) is a type of therapy commonly used to treat anxiety and depression. It can help you manage overwhelming problems by changing the way you think and behave in a positive and practical way. Typically this is done in sessions with a therapist. For more information about CBT, click here.


electronic CBT (eCBT), uses the same principals but in a system you can access and use by yourself. It uses a virtual dialogue, provides information on depression, gives you exercises, methods and techniques and supports you with e-mails or text messages.

What is deprexis®?


deprexis® is a CE marked medical device largely based on cognitive behavioral therapy (CBT) to help cope with symptoms of depression.

It is designed to help you change certain thinking habits and behaviors that contribute to depression through an online 90-day program.

How does deprexis® work?


deprexis® is based primarily on the methods of cognitive behavioral therapy (CBT). The overall aim is to teach you useful skills you can apply in everyday life to overcome depression.

It contains 10 modules, plus a summary module, which help you build coping skills to address negative thoughts, behaviors, social situations and problem solving.

How is deprexis® different from mindfulness and other similar apps?


Unlike most wellness apps, deprexis® is a CE marked medical device developed by leading experts in medicine and psychology. It is the world’s most researched digital therapy program for depression, and has been clinically shown to reduce depressive symptoms as well as improve self-esteem and quality of life.(1-13)

Why do I need a prescription?


deprexis® is a medical device, so your doctor will need to weigh up the alternatives and make sure it is the right option for you.

What technical skills do I need to use deprexis®?


No special computer or technical skills are required to use the deprexis® online therapy support program.

Can I combine deprexis® with medication?


Yes, deprexis® can be combined with medications (such as antidepressants). You should not discontinue taking your prescribed medications unless advised by your doctor.

Can I reuse my deprexis® access or share it with a third party?


No. Unfortunately, reusing your deprexis® access is not possible.

deprexis® is an interactive, personalized, online therapy program that lasts 90 days. It learns about you, suggests exercises tailored to your needs and responds individually to your responses. That is why deprexis® cannot and should not be passed on to third parties.

Can I use deprexis® on my phone?


Yes, you can use deprexis® on many internet-enabled devices such as notebooks, PCs, smartphones or tablets.

You can also switch between different devices at any time, meaning you can use deprexis® on your phone or tablet while you are on the move – for example if you are listening to an audio exercise.

The following internet browsers are supported:

Notebook or PC:

  • Mozilla Firefox (current version)
  • Google Chrome (current version)
  • Edge (current version)
  • Windows Internet Explorer 11 (current version)
  • Safari (current version)

Smartphone or Tablet:

  • Google Chrome (current version)
  • Mobile Safari (current version – iPhone, iPad, iPod Touch)

How much time will I need to spend on deprexis®?


You can use deprexis® at your own pace.

Experience shows that it is beneficial to use the program 1–2 times a week for at least 30 minutes. You should also take time to incorporate the techniques and exercises into your daily routine.

Of course, you can also use deprexis® more frequently if you want to.

Please also consult your doctor or therapist on this topic.

Do I receive any support from deprexis® beyond the 90 days?


deprexis® is not designed to be a long-term therapy, but aims to help you overcome depression and improve your ability to self-manage.

You will be given hints, tips and support to help you cope in your everyday life. There are materials that can be printed out and used even after completing deprexis®.

If further support with deprexis® seems useful after 90 days, you may want to buy the program again and go through it again. For this, a new registration is required, which is again subject to a charge. If you want to restart using deprexis® you can ask your doctor for a new access code.

* please note, if you want to buy a second access code you will to create a new account, and provide the system with a different e-mail address from your first registration. The settings of the first 90 days will not be transferred to the new account.

Is deprexis® the right therapy for me?


deprexis® can be compared to psychotherapy, in particular cognitive behavioural therapy (CBT), for people with mild-to-moderate depression.

By learning CBT skills, you are empowered to recognize and alter thinking habits and behavioral patterns that can create and maintain depression.

Some people may find that dealing with troubling issues is difficult or upsetting. If that is the case, you are encouraged to take a break, stop using the program, and talk to your doctor or therapist.

Are there any risks or side-effects?


It is possible that not everyone will benefit from using deprexis®, which may trigger feelings of disappointment.

It is also possible that some people may find it difficult to deal with upsetting subjects.

If working with the program becomes too upsetting, you should take a break, stop using the program and talk to your doctor or therapist.

Not every exercise is equally suitable for everyone. If an exercise proves difficult for you, makes you feel uncomfortable, or affects you negatively, you should not continue with that exercise.

Should you experience any side effects while using deprexis®, you should inform your doctor or therapist immediately or send an email to

Is deprexis® CE marked? What is CE marking?


Yes, deprexis® is CE marked. This means that deprexis is effective and safe according to standards for products sold within the European Economic Area (EEA).

Where does the deprexis® content come from?


deprexis® was developed by a team of psychologists, physicians, software engineers and communication experts.

All of the content is based on findings from research on depression and on practical real-life experience from working with people with depression.

Here is a list of some of the scientific literature that was used in developing the program:


Addis ME, Truax P, Jacobsen NS. Why do people think they are depressed?: The Reasons For Depression Questionnaire. Psychotherapy: Theory, Research, Practice, Training 1995;32(3):476-483.

Baer RA. Mindfulness training as a clinical intervention: A conceptual and empirical review. Clinical Psychology: Science and Practice 2003;10(2):125-143.

Beck JS. Cognitive therapy: Basics and beyond. New York: The Guilford Press; 1995.

Beck AT, Rush AJ, Shaw BF, et al. Cognitive therapy of depression. New York: Guilford Press; 1979.

Bono G, McCullough ME. Positive responses to benefit and harm: Bringing forgiveness and gratitude into cognitive psychotherapy. Journal of Cognitive Psychotherapy 2006;20(2):147-158.

Brandt H, Grose S. Weniger Stress durch Meditative Entspannung, Audio-CD mit Begleitheft, Entspannungsübungen zum Wohlfühlen mit Anleitungen zur Meditation der Achtsamkeit.(Audiobuch). Hannover: Henrik Brandt Verlag; 2005.

Davis M, Robbins Eshelman E, McKay M. The relaxation and stress reduction workbook, 5th ed. Oakland, CA: New Harbinger; 2000.

Deci EL, Ryan RM. The “what” and “why” of goal pursuits: Human needs and the self-determination of behavior. Psychological Inquiry 2010;11(4):227-268.

Dimidjian S, Hollon SD, Dobson KS, et al. Randomized trial of behavioral activation, cognitive therapy, and antidepressant medication in the acute treatment of adults with major depression. Journal of Consulting and Clinical Psychology 2006;74(4):658-670.

Dunn AL, Trivedi MH, Kampert JB, et al. Exercise treatment for depression: Efficacy and dose response. American Journal of Preventive Medicine 2005;28(1):1-8.

Epstein S. Cognitive-experiential self-theory. In: Barone DF, Hersen M, Van Hasselt VB, (Eds.) Advanced personality. New York, NY: Plenum Press; 1998. p. 211-238.

Esterling BA, L’Abate L, Murray EJ, et al. Empirical foundations for writing in prevention and psychotherapy: Mental and physical health outcomes. Clinical Psychology Review 1999;19(1):79-96.

Gable SL, Reis HT, Impett EA, et al. What do you do when things go right? The intrapersonal and interpersonal benefits of sharing positive events. Journal of Personality and Social Psychology 2004;87(2):228-245.

Gortner ET, Gollan JK, Dobson KS, et al. Cognitive-behavioral treatment for depression: Relapse prevention. Journal of Consulting and Clinical Psychology 1998;66(2):377-384.

Grawe K. Neuropsychotherapie. Göttingen: Hogrefe; 2004.

Hayes SC, Strosahl KD, Wilson KG. Akzeptanz und Commitment Therapie: Ein erlebnisorientierter Ansatz zur Verhaltensänderung. München: CIP; 2004.

Hayes SC, Smith S. Get out of your mind and into your life: The new acceptance and commitment therapy. Oakland, CA: New Harbinger; 2005.

Hill CE. Dreams and therapy. Psychotherapy Research 1996;6:1-15.

Hill CE, Crook-Lyon RE, Hess SA, et al. Prediction of session process and outcome in the Hill dream model: Contributions of client characteristics and the process of the three stages. Dreaming 2006;16:159-185.

Jacobson NS, Dobson KS, Truax PA, et al. A component analysis of cognitive-behavioral treatment for depression. Journal of Consulting and Clinical Psychology 1996;64(2):295-304.

Kabat-Zinn J. Mindfulness-based interventions in context: Past, present and future. Clinical Psychology: Science and Practice 2003;10(2):144-156.

Kabat-Zinn J, Kesper-Grossman U. Stressbewältigung durch die Praxis der Achtsamkeit.Freiamt im Schwarzwald: Arbor Verlag; 1999.

Keyes CLM, Haidt J. Flourishing: Positive psychology and the life well-lived. Washington, DC: American Psychological Association; 2003.

Klerman G, Weissman M, Rounseville B, et al. Interpersonal psychotherapy of depression. New York: Basic Books; 1984.

Martell CR, Addis ME, Jacobson NS. Depression in context: Strategies for guided action. New York: Norton; 2001.

McQuaid JR, Carmona PE. Peaceful mind: Using mindfulness and cognitive behavioral psychology to overcome depression. Oakland, CA: New Harbinger; 2004.

Meyer B, Garcia-Roberts L. Congruence between reasons for depression and motivations for specific interventions. Psychology and Psychotherapy: Theory, Research and Practice 2007;80(4):525-542.

Morris J. The dream workbook: Discover the knowledge and power hidden in your dreams. New York: Fawcett Crest; 1985.

Mynors-Wallis LM. Problem-solving treatment for anxiety and depression: A practical guide. Oxford, UK: Oxford University Press; 2005.

Mynors-Wallis LM, Gath DH, Lloyd-Thomas AR, et al. Randomised controlled trial comparing problem-solving treatment with amitriptyline and placebo for major depression in primary care. British Medical Journal 1995;310(6977):441-445.

Mynor-Wallis LM, Gath D, Day A, et al. Randomised controlled trial of problem-solving treatment, antidepressant medication and combined treatment for major depression in primary care. British Medical Journal 2000;320(7226):26-30.

Nezu A. Efficacy of a social problem-solving therapy approach for unipolar depression. Journal of Consulting and Clinical Psychology 1986;54(2):196-202.

Pennebaker JW. Writing to heal. Oakland, CA: New Harbinger; 2004.

Pennebaker JW. Opening up: The healing power of expressing emotions. New York, NY: Guilford Press; 1997.

Reis HT, Sheldon KM, Gable SL, et al. Daily well-being: The role of autonomy, competence, and relatedness. Personality and Social Psychology Bulletin 2000;26(4):419-435.

Richardson CR, Avripas SA, Neal DL, et al. Increasing lifestyle physical activity in patients with depression or other serious mental illness. Journal of Psychiatric Practice 2005;11(6):379-388.

Ryan RM, Deci EL. The darker and brighter sides of human existence: Basic psychological needs as a unifying concept. Psychological Inquiry 2000;11(4):319-338.

Segal ZV, Williams S, Teasdale J. Mindfulness-based cognitive therapy for depression: A new approach to preventing relapse. New York: Guilford; 2002.

Seligman MEP. Der Glücks-Faktor: Warum Optimisten länger leben. Bergisch-Gladbach: Verlagsgruppe Lübbe; 2005.

Seligman MEP, Csikszentmihalyi M. Positive psychology: An introduction. American Psychologist 2000;55(1):5-14.

Seligman MEP, Rashid T, Parks AC. Positive psychotherapy. American Psychologist 2006;61(8):774-788.

Seligman MEP, Steen TA, Park N, et al. Positive psychology progress: Empirical validation of interventions. American Psychologist 2005;60(5):410-421.

Sheldon KM, Williams G, Joiner T. Self-determination theory in the clinic: Motivating physical and mental health. New Haven, CT: Yale University Press; 2003.

Sheldon KM, Niemiec CP. It’s not just the amount that counts: Balanced need satisfaction also affects well-being. Journal of Personality and Social Psychology 2006;91(2):331-341.

Sheldon KM, Elliot AJ, Kim Y, et al. What is satisfying about satisfying events? Testing 10 candidate psychological needs. Journal of Personality and Social Psychology 2001;80(2):325-339.

Snyder CR, Lopez SJ. Handbook of positive psychology. London: Oxford University Press; 2002.

Stetter F. Entspannungsverfahren. Wirksame Komponenten psychotherapeutischer und psychiatrischer Behandlung. Psychotherapeut 2004;49(4):281-291.

Suinn RM. Anxiety management training: A behavior therapy. New York, NY: Plenum Press; 1990.

Trösken AK, Grawe K. Inkongruenzerleben aufgrund brachliegender und fehlender Ressourcen: Die Rolle von Ressourcenpotentialen und Ressourcenrealisierung für die psychologische Therapie. Verhaltenstherapie und Psychosoziale Praxis 2004;36:51-62.

Williams M, Teasdale J, Segal Z, et al. The mindful way through depression: Freeing yourself from chronic unhappiness. New York, NY: Guilford Press; 2007.

Further reading


deprexis® is more than a self-help book, as it responds to you personally.

Of course, there are also very good self-help books that you can read to help you cope with depression:

Achor S. The happiness Advantage: The seven principles of positive psychology that fuel success and perfomance at work. New York: Crown Business; 2010.

Addis ME, Martell CR. Overcoming depression one step at a time. The new behavioral activation approach to getting your life back. Oakland: New Harbinger Publications; 2004.

Burns DD. Feeling good: The new mood therapy revised and updated. New York: Avon Books; 1999.

Davis M, Eshelman ER, McKay D. The relaxation & stress reduction workbook. 6th ed. Sydney: New Harbinger Publications; 2008.

Fast JA, Preston JD. Get it done when you’re depressed : 50 strategies for keeping your life on track. New York: Penguin Group (USA) Inc.; 2008.

Greenberger D, Padesky CA. Mind over mood: A cognitive therapy treatment for clients: Cognitive treatment therapy manual for clients. New York: Guilford Press; 1995.

Hayes SC, Smith S. Get out of your mind and into your life. The new acceptance and commitment therapy. Oakland: New Harbinger Publications; 2005.

Jeffers S. Feel the fear … and do it anyway. New Ed. London: Arrow; 2011.

Kabat-Zinn J. Guided mindulfness mediation [Audiobook]. Louisville: Sounds True; 2005.

Kabat-Zinn J. Wherever you go, there you are: Mindfulness meditation in everyday life. New York: Hyperion Books; 2005.

Lyubomirsky S. The how of happiness: A new approach to getting the life you want. London: Penguin Books; 2008.

Morris J. The dream workbook: Discover the knowledge and power hidden in your dreams. London: Little, Brown and Company; 2002.

Pennebaker JW. Opening up. The healing power of expressing emotions. New York: The Guilford Press; 1997.

Quinn P. Freedom from fear: Taking back control of your life and dissolving depression. Lake George: Peyton Quinn Publishing; 2004.

Seligman MEP. Authentic happiness. Using the new positive psychology to realize your potential for lasting fulfilment. London: Nicholas Brealey Publishing; 2003.

Seligman MEP. Learned optimism: How to change your mind and your life. New York: Vintage Books; 2006.

Williams C. Overcoming depression and low mood. A five areas approach. 3rd ed. London: Hodder Arnold; 2012.

Williams M, Teasdale J, Segal Z, et al. The mindful way through depression. Freeing yourself from chronic unhappiness. 1st ed. New York: The Guilford Press; 2007.

Young JE, Klosko JS, Beck AT. Reinventing your life: The breakthrough program to end negative behavior … and feel great again. New York: Penguin Group (USA) Inc.; 1994.


What about data protection - is my data secure?


We take the protection of your personal data, e.g. your email address and other details, very seriously, and only ask for these to facilitate your use of deprexis®. Your personally identifiable data will not be given to third parties nor be used for marketing purposes. Your data is saved according to data protection regulations. More information about data protection can be found in the deprexis® terms and conditions.

Data transmission takes place over a secure HTTPS internet connection; your details are encrypted by SSL.

deprexis® is not installed on the end devices as a program, but you can only access the program online, no data is stored on the end device.


How do I use deprexis®?


To use deprexis®, simply register with your access code at deprexis registration then follow the instruction.

Registration can be anonymous; you only need an e-mail address and an individual password.

If you want to register anonymously, use an email address that does not contain personal data (name, year of birth, etc.).

After registering, you can use deprexis® around the clock, anytime and anywhere you like.

I am a therapist – how can I use deprexis® to benefit my patients?


deprexis® aims to enhance the availability of psychotherapeutic care and support face-to-face psychotherapy. In fact, a recent study has shown that when deprexis® is added to psychotherapy, the improvement is significantly higher compared to psychotherapy alone.

As patients can use deprexis® in their own time, this may allow therapists to use their personal sessions in a more focused manner in order to work on clients’ individual issues.

I can’t log in. What am I doing wrong?


If you want to access deprexis® for the first time, please click ‘Register’ on the deprexis® homepage and insert your access code.

After you have registered you can log in via the ‘Login’ button with the login details you generated during the registration process.

I cannot sign in, even though I am doing everything exactly the way I usually do.


If you cannot log in, the easiest way to access your account is to click ‘New password’ and to generate a new password.

If you’ve forgotten your e-mail address you can also use your access code to find your account.

The answer options in the sessions do not always fit my situation. What should I do?


It can happen that you won’t find the answer that fits you exactly. This is normal and you do not need to worry about it.

In this case, simply choose the answer that seems the best to you. deprexis® will then attempt to act on this and to direct the conversation in the right direction.

Do not worry: deprexis® is built in a way that means you won’t miss out on any information that could be helpful to you.

Where can I change my personal details?


If you want to choose a new name or change your email address or mobile phone number, you can do that here: Settings


You can choose a new password here: Password


You can edit your gender and age details here: Personal

Can I download the audio files?


Unfortunately, it is not possible to download the audio files directly to your electronic device.

However, you can listen to your audio files whenever and as often as you want in “Your area” and under “Your exercises”.

Where can I find deprexis®?


deprexis® is a browser-based program, so you can access it from anywhere with internet access, any time. You can find deprexis® here:

Why can't I go back and choose another answer in chats?


The idea behind deprexis® is to conduct a dialogue or “chat” that simulates a real conversation.

We want to make the dialogue feel as real as possible for you. So, deprexis® does not consist of a series of standard pages one after another – which is the case for most web programs – but instead responds to your answers dynamically, according to what you choose. Going “back” in your browser doesn’t make sense with deprexis®.

However, if you want to, you can repeat sessions: as soon as you have completed all of the deprexis® chats, they become available to you again.

You can then repeat them as often as you wish. That way you can also review any thoughts and suggestions you might want to look at again.

Why do I need to confirm my email address and mobile number?


If you confirm your email address and mobile number, we can help you if you lose your password, and we can also send you emails and text messages with helpful suggestions and tips for dealing with depression.

Apart from this, confirming your email address and mobile number helps to ensure the security of your data.

In case you haven’t done it yet – please confirm your email address and mobile phone number here: Settings

How do I register with deprexis®?


To use deprexis® , you must register with the access code at deprexis registration, then follow the instructions of the program. The registration can be anonymous, you only need an e-mail address and an individual password. If you want to register anonymously, use an email address that does not contain personal data (name, year of birth, etc.). After registering, you can use deprexis® around the clock – flexibly and independently.

Why do you need my mobile number?


If you enter your number you will receive a daily text message from deprexis®, which many users have found helpful. You can enter this directly when you register or choose to do so in your deprexis® settings later when you log in.

The text message service is free of charge in the country in which you complete your registration. For use outside of this country you are responsible for roaming and other equivalent charges.

Naturally, you can choose to end or pause the sending of deprexis® text messages, for example to avoid roaming charges if you are travelling abroad.

To do this, simply delete your mobile phone number in your deprexis® settings.

If you want to receive text messages again later, enter your mobile phone number again and confirm this.

Your mobile number will be handled confidentially and will only be used to send you deprexis® text messages. It will not be given to third parties or used for marketing purposes. Storage is done in accordance with the required data protection regulations.

Please note that deprexis® text messages are not available for every country and language.

How can I be sure of my privacy?


Data protection is one of our top priorities. The processing of personal data of a data subject shall always be in line with the General Data Protection Regulation (GDPR), and in accordance with the country-specific data protection regulations (i.e. BDSG) applicable to GAIA AG. You can read our privacy policy here.


Can I contact you in an emergency?


In emergencies or when needed, contact your doctor or psychotherapist.

Further help is available under the known emergency numbers.

Police: 999
Emergency ambulance: 995
Institute of Mental Health helpline: 6389 2222
Suicide prevention hotline: 1800 221 4444

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